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Next Generation
Antibody Diagnostics

Our peptide-based, precision immunology platform delivers stronger signal and eliminates background noise, enabling clinical-grade assays with unmatched reproducibility.

From discovery to diagnostics, we turn peptide science into real-world solutions.

Epitope mapping of SARS-CoV-2

Epitope mapping of SARS-CoV-2

Biotome’s Epitope Mapping Pipeline Discovers Unique Diagnostic Targets for SARS-CoV-2

Biotome’s peptide augmentation technology ensures structured orientation and enhanced antibody accessibility.

Biotome’s peptide augmentation technology ensures structured orientation and enhanced antibody accessibility.

Patent Filed: Peptide Augmentation Technology

Make Peptides Work

Poor binding, weak signal, high background, crazy conjugation tricks... Sound familiar?

For years, peptides have promised low cost and high precision, but fail when translating results to the real world. Our patent-pending approach makes peptides bind, boosts signal, and eliminates background.

We make peptides work.

In Development

1

Helitope
Gastric Cancer Risk

Identify patients at greatest risk of developing gastric cancer

2

PreACT
Preeclampsia Risk

Risk assessment for preeclampsia in early pregnancy

Services

Epitope Mapping & Antibody Characterisation

>100k peptides
Whole proteome or protein specific
From sequences, variants
Linear, conformational and discontinuous
Isotyping and subclassing
Specificity & cross-reactivity profiles
Permutation/alanine scans for critical residues & tolerance

Peptide Optimisation and Assay Development

Full-service, from epitope discovery to prototyping
Peptide optimisation, synthesis and conjugation
Matrix screening (serum, plasma, DBS, saliva)
Multiplex panel development
Lab-based and point-of-care platforms
Freedom-to-operate, IP strategy and patent guidance

Research & Collaborations

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Idiopathic Pulmonary Fibrosis

Investigating how B-cells and antibodies drive disease and turning those insights into earlier, specific diagnosis.

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Rheumatic Heart Disease

Characterising antibody responses for diagnostics and vaccines, and stratifying patients in low-resource settings.

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Multiple Sclerosis

Mapping antibody and epitope signatures and tying them to T-cell–driven pathology to sharpen diagnosis and stratify progression.

Supporters & Collaborators

Thank you to our supporters, investors, collaborators, and grant funders for making this work possible!

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